Technology and Industry: RSNA 2003 preview; Nobel Prize awarded for discoveries leading to MRI

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Nobel Prize awarded for MRI

The Nobel Assembly at Karolinska Institute has awarded The Nobel Prize in Physiology or Medicine for 2003 to Paul C. Lauterbur, PhD and Sir Peter Mansfield, PhD for their discoveries leading to the development and clinical application of magnetic resonance imaging (MRI).

In announcing the award, the Institute noted, "This year's Nobel Laureates in Physiology or Medicine have made seminal discoveries concerning the use of magnetic resonance to visualize different structures. These discoveries have led to the development of modern MRI, which represents a breakthrough in medical diagnostics and research."

Dr. Lauterbur, professor and director of the Biomedical Magnetic Resonance Laboratory at the University of Illinois at Urbana, is credited with discovering "the ability to create a 2D picture by introducing gradients in the magnetic field. By analysis of the characteristics of the emitted radio waves, he could determine their origin. This made it possible to build up 2D pictures of structures that could not be visualized with other methods."

Sir Peter Mansfield of the Magnetic Resonance Centre at the University of Nottingham, England, is credited with further developing "the utilization of gradients in the magnetic field. He showed how the signals could be mathematically analyzed, which made it possible to develop a useful imaging technique. Mansfield also showed how extremely fast imaging could be achievable. This became technically possible within medicine a decade later."

"Paul Lauterbur's work is perhaps the most significant medical diagnostic discovery of the 20th century," said Nancy Cantor, the chancellor of the University of Illinois' Urbana campus. "Every patient who undergoes a noninvasive medical imaging procedure should thank Paul. His work has led to revolutionary insights into the functions of the brain and the workings of the human body."

"MRI has had a revolutionary impact on medicine throughout the world," said Sir Colin Campbell, vice-chancellor at the University of Nottingham. "This award is testament to Sir Peter's pioneering work."

In 1987, Dr. Lauterbur was awarded the Radiological Society of North America (RSNA) Gold Medal for his pioneering work in the field of MRI.

RSNA 2003

The upcoming 89 th Scientific Assembly and Annual Meeting of the RSNA (RSNA 2003) once again promises to be a showcase for the latest innovations in radiology.

To be held November 30 through December 5 in Chicago, IL, the scientific program will feature 2161 leading-edge presentations. "What the scientific program highlights is cutting-edge research and the state-of-the-art in radiology. It also shows what the immediate future will look like," said scientific program committee chairman George S. Bisset, III, MD, vice-chair of the department of radiology at Duke University Medical Center, Durham, NC.

Many of the presentations will focus on a number of emerging trends, including multidetector computed tomography (CT) applications, virtual gastroscopy, 3D volumetric measurement, multimodality imaging, emergency radiology, and 3-Tesla MRI. In addition, noted Bisset, "There are a lot more functional imaging studies than we saw last year, particularly in neuroradiology with diffusion imaging and perfusion imaging."

The technology that makes these advanced procedures possible will also be on display from >630 companies throughout the nearly 440,000 square feet of exhibit space. Of these, 88 companies will exhibit at RSNA for the first time this year.

SonoSite

SonoSite (Booth 3944) will unveil its new mobile ultrasound (US) system, Titan, at this year's meeting. The unit, which can be handheld or docked into a cart, is based on the company's ASIC (Application Specific Integrated Circuit) chip technology, with three such chips housed on a single circuit. The result is a compact unit that boots up in <14 seconds.

The system includes color power Doppler, pulse wave Doppler, tissue harmonic imaging, M-mode, SiteLink, on-board DICOM, and a large LCD screen. The system allows the user to have three transducers always attached and the ability to switch between transducers in <6 seconds.

With the Titan Mobile Docking system, the unit can be docked to a cart, which provides on-board storage and connectivity to internal information systems, including PACS. The product is designed to allow radiologists to provide diagnostic-quality mobile US throughout the hospital. Titan can be used for a variety of US applications including musculoskeletal, vascular, abdominal, general thoracic, obstetric, gynecologic, pediatric, and neonatal head and abdomen imaging.

Siemens Medical Solutions

Siemens Medical Solutions (Booth 1929) will introduce Speed4D CT technology. The company calls this a "paradigm shift in CT tube technology, dose, and workflow management to enable advanced utilization of cutting-edge multislice CT technology and integration of sophisticated imaging applications." No further information was available at press time.

Siemens will also feature its first digital ceiling-mounted universal angiography C-arm system equipped with flat-panel detector technology, the Axiom Artis dTA. This system was designed to provide 3D image quality and network connectivity for vascular and nonvascular diagnostic and interventional procedures.

Siemens will also feature:

* The Acuson Sequoia's Matched Response Technology using the company's proprietary Native Patient Specific Imaging to detect, measure, and adapt, in real time, to a patient's individual acoustic properties;

* New transducer and acoustic technologies for the Sonoline Antares US system;

* The new c.cam dedicated cardiology gamma camera, which includes a reclining chair to increase patient comfort and reduce movement;

* The Mammomat Novation (DR) digital mammography system, which, when used in combination with Opdima, becomes an all-in-one unit to support an entire digital mammography work-up, and

*The Siremobil Iso-C(3D) mobile C-arm with intraoperative 3D imaging capabilities and the open interface NaviLink, which is compatible with nearly all navigation systems offering direct 3D navigation in the operating room.

Orex

Orex (Booth 4450) will showcase several new features of its compact computed radiography (CR) system (Figure 1), particularly its increased processing speed and decreased footprint.

New enhancements include an increased throughput of up to 75 cassettes an hour with a single scanner and up to 150 plates per hour on a dual scanner. With regular and low-dose speeds of 100, 200, and 400, the system's resolution modes range from 5.8 to 20 pixels/mm. The standard acquisition matrix is 2000 * 2500 pixels, and an option for 4000 * 5000 pixels is available. The new system, which weighs 44 lbs., has a 50% smaller footprint than the previous model. An optional programmable key offers customized system configuration for specific applications.

The company will also display existing products for specific applications, including a radiotherapy cassette that captures high-quality mega-voltage portal images for treatment verification, as well as kilo-voltage images for treatment simulation. The company's range of scanner products, including the new PcCR 1417 ACLxy, which scans up to 75 plates per hour, and the dual-reader RAIS 2 ACLxy (Redundant Array Integrated System), which scans 150 plates per hour, will also be featured.

Philips Medical Systems

Philips Medical Systems (Booth 7132) will exhibit a full range of imaging modalities.

For X-ray, the company will feature the Eleva line of X-ray systems: the MultiDiagnost Eleva, which provides multifunctionality; the EasyDiagnost Eleva conventional RF system; and the OmniDiagnost Eleva multifunctional, remote-controlled X-ray system.

The company will also feature its complete line of CT products, including 2-, 6-, 10-, and 16-slice scanners, with an emphasis on innovations in detector design, signal conversion, data transfer, reconstruction, and tube technology.

The Philips EnVisor Ultrasound system offers several new features, including the QuickSCAN intelligent features, three new transducers, online obstetric, trending, and an expanded international language library.

In the field of information technology, Philips will highlight the latest version of its ViewForum technology. The system provides users with automated and protocoled tools to view complex CT and MR image series at a speed suitable for clinical routine. ViewForum is available on modality workstations and consoles and is also integrated into the Philips PACS workstations.

Philips Nuclear Medicine/PET will showcase the latest version of SKYLight, a gantry-free gamma camera now with concurrent imaging, as well as the new MOSAIC, an advanced "small bore" animal positron-emission tomography (PET) system. The company's open-layout, combined PET and CT system, Gemini, and Syntegra multimodality software, will also be shown.

Kodak Health Imaging

Kodak Health Imaging (Booth 2729) will be highlighting three new Professional Services offerings. The company's Storage and Archive Services (SAS) provide an ASP offsite storage service, data migration, and disaster recovery capabilities. The Kodak Healthcare Integration Services link a Kodak PACS and radiology information system (RIS) with existing enterprise-wide RAID storage devices, as well as hospital information systems (HIS)/RIS systems, and also provides modality integration between RIS and PACS. Kodak Secure E-mail Service encrypts e-mail messages and their attachments.

The company will also present the latest version of the DirectView PACS System 5 (Figure 2), which includes integrated 3D utilities, enterprise-wide reporting enhancements, and a teaching file utility. RSNA 2003 will also be the American launch site for the company's Radiology Information System 2010 (RIS 2010). The RIS 2010 integrated platform addresses all aspects of image and information workflow.

Kodak will also preview, as a work-in-progress, a computer-aided detection (CAD) system for mammography based on technology acquired from MiraMedica, Inc.

E-Z-EM

E-Z-EM (Booth 4519) will introduce two new products at RSNA 2003: the EMPOWERCTA Injector System and VoLumen, an oral contrast agent.

The EMPOWERCTA Injector System is a double-barrel CT injector designed for advanced CT procedures that require the use of a saline chase. Based on the EMPOWERCT design and technology, the new injector offers all of the features of the original system, including patented extravasation detection, tilt sensor lock-out, arming at the injector, flexibility, and expandability, as well as the double-barrel design.

VoLumen, the company's new oral contrast agent for multidetector CT studies of the abdomen and pelvis, allows the radiologist to control the transit of the agent through the gastrointestinal tract. This allows the user to predict its location and achieve better bowel lumen distention. According to E-Z-EM, this allows the radiologist to "perform a single study of the abdominal and pelvic regions to investigate all organs, vasculature, and surrounding structures simultaneously."

CADx

CADx (Booth 6749) will highlight several works-in-progress at RSNA 2003. One is a CAD system that works with analog and digital mammography systems simultaneously. The Second Look AD is designed to meet the needs of facilities with both film-based and digital mammography. This system will offer the same functionality as the original film-based Second Look and adds digital capabilities to work with new full-field digital mammography (FFDM) systems. Films digitized using this system can be exported in DICOM format and stored in the same manner as FFDM images without the need to touch the films again. Currently installed Second Look analog systems will be field upgradable to Second Look AD.

Another future offering that will be previewed this year is Second Look CT Colon. This system will utilize 2D slices and 3D volume renderings to mark objects within the colon. The markers will then be displayed on the reconstructed colon landscape view. The system will provide custom measurements and characterizations of the objects found, and provide a comparison of the object to a library of similar objects. In addition, the company notes, "the system could subsequently provide registration cueing with an optical colonoscope to help guide the physician to the target for removal."

Finally, don't forget--when you are at RSNA 2003, stop by Booth 7811 and visit Applied Radiology .

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