Infant with vomiting

4 week old female with onset of projectile nonbilious vomiting.

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Diagnosis

Hypertrophic pyloric stenosis.

Findings

Sonographic images of the upper abdomen show thickening and elongation of the pylorus, consistent with hypertrophic pyloric stenosis.

Discussion

As the name implies, hypertrophic pyloric stenosis represents a progressive hypertrophy of the pylorus muscle, resulting in gastric outlet obstruction. The disease presents in infancy, usually between the ages of 1-2 months, with progressive onset of projectile nonbilious vomiting. On physical examination, a palpable lump (or "olive") and reverse peristalsis may be apparent in the right upper quadrant or epigastrium. Imaging may include plain films, ultrasound, and occasionally fluoroscopy. Plain films may show gaseous gastric distention or mottled gastric contents, as well as diminished air distal to the pylorus. Ultrasound has become the imaging mainstay in the diagnosis of hypertrophic pyloric stenosis. Sonographic findings include thickening (>4mm) and elongation (>14mm) of the pylorus muscle (Note that these values vary from institution to institution). The thickness measurements should be performed on the hypoechoic (muscular) portion a single wall, which is a more sensitive measurement and the total diameter of the pylorus. Ultrasound images, as in this case, may demonstrate shouldering of the interim body hypertrophic muscle. Real-time imaging aid in the diagnosis by demonstrating diminished or absent passage of gastric contents through the pylorus, as well as vigorous gastric peristalsis. Note that pseudo-thickening can be seen if the pylorus is imaged in an oblique projection. Treatment is surgical (pyloromyotomy).

Provenzale JM, Nelson RC. Duke Radiology Case Review. pp 424-425. Lippincott-Raven , Philadelphia, 1998.

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