65-year-old female with altered mental status

David Clopton, MD, Department of Radiology, University of Virginia Health Systems, Charlottesville, VA

A 65-year-old female with unknown medical history presents to the emergency department with an altered mental status after a motor vehicle accident. Her family reports she did have some behavioral changes in the preceding weeks.

What is the most likely diagnosis?

Diffuse axonal injury
Fabry disease
Fahr’s disease
Manganese toxicity


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