http://www.appliedradiology.com RSS Feed on Applied Radiologyhttp://www.appliedradiology.com//Issues/2005/01/Supplements/Applications-of-quantitative-T1,-T2,-and-proton-density-to-diagnosis.aspxQuantitative magnetic resonance imaging (Q-MRI) differs sharply from conventional directly acquired MRI in that objective measures (such as the trio of basic MR properties: T1, T2, and proton density[PD]) are used for analysis as well as further postprocessing rather than relative signal intensities. This paper will recount a brief history of the origins and applications of Q-MRI for measurement of T1 and T2 relaxation times and PD, as well as discuss the basic theoretical underpinnings. A variety of postprocessing options as well as a review of the scientific literature regarding clinical applications of these techniques over the past 30 years are addressed.Wednesday, 19 Jan 2005 15:57:56 GMT