http://www.appliedradiology.com RSS Feed on Applied Radiologyhttp://www.appliedradiology.com//Issues/2002/10/Supplements/Use-of-Low-molecular-weight-Heparin-During-Percutaneous-Coronary-Intervention.aspxLow-molecular-weight heparins (LMWHs) have enjoyed increasing use in clinical cardiology. Their safety and efficacy in the management of patients with acute coronary syndrome has been documented by multiple large, prospective, randomized trials. Low-molecular-weight heparins display pharmacodynamic properties that allow for a predictable and reliable level of anticoagulation. Thus, extending their use during percutaneous coronary intervention (PCI) seems attractive. Data are now emerging on the procedural use of LMWHs for PCI. Although limited, initial data appears encouraging that LMWHs can be used safely and effectively in patients undergoing PCI with or without concurrent glycoprotein IIb/IIIa receptor use. This article will review the available literature on the procedural use of LMWHs with particular attention to pharmacodynamics, safety, and efficacy.Monday, 03 Mar 2003 16:28:39 GMT