Recurrence of colorectal cancer, mucinous type

Tuesday, 01 Feb 2005 13:47:46 GMT

The patient is a 64-year-old Hispanic man who underwent resection of mucinous, moderately well-differentiated adenocarcinoma of the rectosigmoid (Stage T3N1M0; Duke's C) in July 1996. At the time of surgery, his serum carcinoembryonic antigen (CEA) level was 3.5 ng/mL. In December 1997, he had a second surgery for recurrence, after which he completed a course of remote after-loading high-dose-rate irradiation via intraoperative interstitial implant. During a left herniorrhaphy procedure in August 1998, a deep-needle biopsy of the presacral area was performed, revealing mucinous, metastatic colonic adenocarcinoma. Although serum CEA assay results were within normal limits (2.0 ng/mL); the tumor tissues were CEA-membrane positive. In the months immediately preceding and following the biopsy, an F-18 fluorodeoxyglucose (FDG) positron emission tomography (PET) scan, magnetic resonance imaging (MRI) study, and a nuclear imaging study with arcitumomab were performed (figures 1 through 3).

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Recurrence of colorectal cancer, mucinous type