http://www.appliedradiology.com RSS Feed on Applied Radiologyhttp://www.appliedradiology.com//Issues/2010/12/Cases/Bisphosphonate-associated-osteonecrosis-of-the-jaw.aspx<p> A 74-year-old man with a history of multiple myeloma and undergoing intravenous zoledroic acid (Zometa^® Novartis Oncology, Basel, Switzerland) therapy from 2003 to 2005 presented with a 3 cm to 4 cm area of exposed, necrotic appearing bone in the right maxilla following a tooth extraction in 2005 (Figure 1). A biopsy was not performed; however, clinical suspicion strongly ruled out metastatic involvement, and findings have remained stable since the patient was administered oral antibiotic and oral antimicrobial rinse therapy. </p>Friday, 17 Dec 2010 16:31:22 GMT