SPECT · PET · Diagnostic Imaging · Molecular Imaging · Nuclear Medicine
SNMMI and QMIC Collaborate to Enhance Quantitative Molecular Imaging
November 11, 2026 · News Release
Source: snmmi.org

The Society of Nuclear Medicine and Molecular Imaging (SNMMI) and the Quantitative Medical Imaging Coalition (QMIC) have formalized a strategic collaboration through a Memorandum of Understanding (MoU) aimed at advancing the standardization, reproducibility, and clinical application of quantitative PET and SPECT imaging worldwide. This partnership leverages the complementary expertise of both organizations to enhance the role of quantitative molecular imaging in multicenter clinical trials and routine clinical practice.
Objectives of the Collaboration
The collaboration will focus on several areas:
- Standardized Imaging Guidelines: The development of harmonized guidelines for PET/CT and SPECT/CT image acquisition, documentation, processing, and analysis.
- Quantitative Imaging Biomarkers: Initiating efforts to advance, validate, and implement quantitative imaging biomarkers for clinical research and patient care across PET/CT and SPECT/CT modalities.
- Scanner and Site Network: Establishing a network of compatible PET/CT and SPECT/CT scanners and clinical sites to adhere to standardized quantitative imaging requirements.
- Biomarker Harmonization: Creating standards for quantifying PSMA Total Tumor Volume in PSMA PET and Metabolic Tumor Volume in FDG PET, alongside guidelines for other related imaging biomarkers.
The MoU emphasizes the continuous development and refinement of quantitative PET/CT guidelines, fostering collaboration between SNMMI's scientific community and QMIC's dedicated Biomarker Committees.
Advancing Reliable Imaging Practices
The intent of this collaboration is to facilitate the shift from qualitative to more objective, quantitative assessments of disease through PET and SPECT imaging. Achieving the full potential of these imaging modalities necessitates harmonized methodologies, validated imaging systems, and consistent technical standards across various clinical sites.
Combining their strengths, SNMMI and QMIC are committed to enhancing the reliability and comparability of quantitative imaging biomarkers, which is crucial in supporting multicenter research and bolstering clinical implementation.
SNMMI is a nonprofit organization dedicated to the advancement of nuclear medicine and molecular imaging, while QMIC strives to promote the use of imaging biomarkers for clinical trials and practice.





